Non-default partitions and upgrades

Hello!

I generally try and run things as a project recommends, but I am
wondering about running different additional partitions (e.g., add
/var/www) or changing partition letter (e.g., move /var to the end for
convenient VPS expansion).

I know it isn't the biggest thing in the world, but would this ever have
an impact on running version upgrades?

Thank you,

Paul